Chemist eugene goldstein biography of mahatma
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Ionization method
Typical
analytes
Sample introduction
Mass range
Method highlights
Electron impact (EI)
Relatively
small, volatile
GC or liquid/solid probe
To 1000 Da
Hard method, versatile, provide structural info
Chemical ionization (CI)
Relatively
small, volatile
GC or liquid/solid probe
To
1000
Da
Soft method, molecular ion peak [M+H]+
Electrospray ionization (ESI)
Peptides, proteins, non volatile molecules
Liquid chromatography or syringe
To 200000 Da
Soft method, ions often multiply charged
Fast atom bombardment (FAB)
Carbohydrates, peptides, organome-
tallics, non volatile molecules
Sample mixed
in viscous matrix
To 6000 Da
Soft method, harder than ESI and MALDI
Matrix Assisted ljusstråle Desorption Ionization (MALDI)
Peptides, proteins, nucleotides
Sample mixed
in solid
matrix
To 500000 Da
Soft method, very high mass
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Published in final edited form as: Arch Gen Psychiatry. 2009 Apr;66(4):355–365. doi: 10.1001/archgenpsychiatry.2009.8
Abstract
Context
Wisdom is a unique psychological trait noted since antiquity, long discussed in humanities disciplines, recently operationalized by psychology and sociology researchers, but largely unexamined in psychiatry or biology.
Objective
We discuss recent neurobiological studies related to subcomponents of wisdom identified from several published definitions/descriptions of wisdom by clinical investigators in the field – i.e., prosocial attitudes/behaviors, social decision-making/pragmatic knowledge of life, emotional homeostasis, reflection/self-understanding, value relativism/tolerance, and acknowledgement of and dealing effectively with uncertainty.
Design
Literature overview focusing primarily on neuroimaging/brain localization and secondarily on neurotransmitters, including their genetic determ
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List of Nobel laureates
The Nobel Prizes (Swedish: Nobelpriset, Norwegian: Nobelprisen) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make outstanding contributions in the fields of chemistry, physics, literature, peace, and physiology or medicine.[1] They were established by the 1895 will of Alfred Nobel, which dictates that the awards should be administered by the Nobel Foundation. An additional prize in memory of Alfred Nobel was established in 1968 by the Sveriges Riksbank (Sweden's central bank) for outstanding contributions to the field of economics. Each recipient, a Nobelist or laureate, receives a gold medal, a diploma, and a sum of money which is decided annually by the Nobel Foundation.[2]
Prize
Different organisations are responsible for awarding the individual prizes; the Royal Swedish Academy of S