Umashree biography of abraham
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pallavi umashree 012
pallavi umashree 012
w in kn/m 20
l in m 10
X in m SFX BMx
0 10 0
1 10 10
2 10 20
3 10 30
4 10 40
5 10 50
6 -10 40
7 -10 30
8 -10 20
9 -10 10
10 -10 0
SFX
15
10
5
SFX
0
1 2 3 4 5 6 7 8 9 10 11
-5
-10
-15
BMx
60
50
40
BMx
30
20
10
0
1 2 3 4 5 6 7 8 9 10 11
slab thickness in m 0.2
span in m 4
density of RCC in kn/m^3 25
LL in kn/m^3 3
DD in kn/m^2 5
factored load in kn/m^2 12
mu in kn-m 24
vu in kn 24
1st proble (2nd unit)
b in mm 300
D in mm 500
d in mm 450
fck in N/m 20
fy in N/m 415
eff cover 50
l in m 6
no of bars 4
dia in mm 20
pie 3.14
Ast in mm 1256
Xu max/d 0.48
Xu /d 0.46654198 DL in KN/m 3.75
xumax/d>xu/d LL in KN/m 20.64559
MR in kn- 164.670245
Wu in kn/ 36.5933878 THE SECTION IS beneath REINFORCED
W IN KN/m24.3955919 THE SUPER IMPOSED LOAD IS 20.64KN
2 problem (2nd unit)
b in mm 250 dead load (density*b*d*1)
d in mm 550 DL in KN/m 3.75
eff cover 50
D in mm 600 W=DL+LL
fck in N/m 20 LL in KN/m 13.08
fy in
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Abstract
Objective
Type 2 diabetes mellitus (T2DM) has emerged as one of the greatest global health challenges of twenty-first century. Visceral obesity is one of the most important determinant of insulin resistance (IR) as well as T2DM complications. Therefore this review focuses on the molecular mechanism of obesity induced inflammation, signaling pathways contributing to diabetes, as well as role of lifestyle interventions and medical therapies in the prevention and management of T2DM.
Method
Articles were searched on digital data base PubMed, Cochrane Library, and Web of Science. The key words used for search included Type 2 diabetes mellitus, obesity, insulin resistance, vascular inflammation and peripheral arterial disease.
Result
Visceral obesity is associated with chronic low grade inflammation and activation of immune systems which are involved in pathogenesis of obesity related IR and T2DM.
Conclusion
Metabolic dysregulation of adipose tissue leads to local hypoxia
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RA=RB 10
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w in kn/m 20
l in m 10
X in m SFX BMx
0 10 0
1 10 10
2 10 20
3 10 30
4 10 40
5 10 50
6 -10 40
7 -10 30
8 -10 20
9 -10 10
10 -10 0
SFX
15
10
5
SFX
0
1 2 3 4 5 6 7 8 9 10 11
-5
-10
-15
BMx
60
50
40
BMx
30
20
10
0
1 2 3 4 5 6 7 8 9 10 11
slab t